Commentaries:
Jamieson, Fausset, and Brown
And ye shall be hated of all men for my name's sake—The universality of this hatred would make it evident to them, that since it would not be owing to any temporary excitement, local virulence, or personal prejudice, on the part of their enemies, so no amount of discretion on their part, consistent with entire fidelity to the truth, would avail to stifle that enmity—though it might soften its violence, and in some cases avert the outward manifestations of it.
but he that endureth to the end shall be saved—a great saying, repeated, in connection with similar warnings, in the prophecy of the destruction of Jerusalem (Matthew 24:13); and often reiterated by the apostle as a warning against "drawing back unto perdition" (Hebrews 3:6, Hebrews 3:13; Hebrews 6:4-6; Hebrews 10:23, Hebrews 10:26-29, Hebrews 10:38-39, etc.). As "drawing back unto perdition" is merely the palpable evidence of the want of "root" from the first in the Christian profession (Luke 8:13), so "enduring to the end" is just the proper evidence of its reality and solidity.
Other Jamieson, Fausset, and Brown entries containing Matthew 10:22:
Isaiah 66:5
Matthew 10:15
Mark 13:13
1 Corinthians 9:24
James 1:4
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