The meaning of Rome in the Bible
(From Easton's Bible Dictionary)

the most celebrated city in the world at the time of Christ. It is said to have been founded BC 753. When the New Testament was written, Rome was enriched and adorned with the spoils of the world, and contained a population estimated at 1,200,000, of which the half were slaves, and including representatives of nearly every nation then known. It was distinguished for its wealth and luxury and profligacy. The empire of which it was the capital had then reached its greatest prosperity.

See more on the meaning of Rome in the Bible:
Rome {International Standard Bible Encyclopedia}
Rome {Hitchcock's Bible Name}

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