The meaning of Rue in the Bible
(From International Standard Bible Encyclopedia)

roo (peganon): One of the plants mentioned in Luke 11:42 as subject to tithe: in the parallel passage, Matthew 23:23, anise and cummin are mentioned. Ruta graveolens (Natural Order, Rutaceae) is the official rue, and a very similar species, R. chalepensis, is indigenous. Rue is a small shrub growing 2 to 4 ft. high with a heavy odor, disagreeable to Westerners, but a favorite with Orientals. A sprig of rue is often fixed on a child's cap or clothes as a kind of charm.

See more on the meaning of Rue in the Bible:
Rue {Easton's Bible Dictionary}

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