The fifth plague struck many of the Egyptian gods and goddesses. The way it did this was because many of the types of livestock: cattle, rams, donkeys, horses, oxen, and camels were sacred to different gods, different cults. And it also struck directly at Pharaoh, who was thought to be a god himself, and the priesthood which was serving the gods. The reason that it struck at them, the Pharaoh and the priests, was that they had the largest herds in all of Egypt. So it made them broke.
Just a few examples here: The cow or bull was sacred to Apis, Ta, Ra, Hathor, Anubis, and Mintu. That is six different gods there. And the ram was sacred to Amon, and Knu. And I do not know what gods the camels and the donkeys were sacred to, but you can bet that there was a sacred to some cult in Egypt. And others of the plagues, we will not go through the other ones, they struck at still other Egyptian deities.