Commentaries:
One of the purposes to which God puts His clouds is to protect His people. The prophet Isaiah provides a good example. The setting of this place-of-safety prophecy is Jerusalem in the last days.
Then whoever is left in Zion and whoever remains in Jerusalem will be called holy, everyone who is recorded among the living in Jerusalem. The Lord will wash away the filth of Zion's people. He will clean bloodstains from Jerusalem with a spirit of judgment and a spirit of burning. The Lord will create a cloud of smoke during the day and a glowing flame of fire during the night over the whole area of Mount Zion and over the assembly. His glory will cover everything. It will be a shelter from the heat during the day as well as a refuge and hiding place from storms and rain. (Isaiah 4:3-6, GOD's WORD Translation)
What provides shelter, refuge, and a hiding place is not so much the “cloud of smoke” itself as it is the presence of God inside the cloud. The linkage of God's glory to the cloud evidences His presence in it: The translators of the Contemporary English Version render verse 5, “God's own glory will be like a huge tent that covers everything.” The Good News Translation has it, “God's glory will cover and protect the whole city.”
Now, of course, there is no question about it: The phrase “a cloud of smoke during the day and a glowing flame of fire during the night” echoes the cloud and pillar of fire of the Exodus and the prolonged wilderness wanderings. Here is one of Scripture's first references to them:
And the LORD went before them by day in a pillar of cloud to lead the way, and by night in a pillar of fire to give them light, so as to go by day and night. He did not take away the pillar of cloud by day or the pillar of fire by night from before the people. (Exodus 13:21-22)
Charles Whitaker
Clouds (Part One): A Really Special Cloud
Other Forerunner Commentary entries containing Isaiah 4:6:
Leviticus 23:42-43
Isaiah 4:3-6