Commentaries:
Barnes' Notes
When his friends - Greek, "they who were of him." Not the apostles, but his relatives, his friends, who were in the place of his nativity.
Heard of it - Heard of his conduct: his preaching; his appointing the apostles; his drawing such a multitude to his preaching. This shows that by "his friends" were not meant the apostles, but his neighbors and others who "heard" of his conduct.
They went out to lay hold on him - To take him away from the multitude, and to remove him to his home, that he might be treated as a maniac, so that, by absence from the "causes" of excitement, he might be restored to his right mind.
They said - That is, common report said; or his friends and relatives said, for they did not believe on him, John 7:5. Probably the enemies of Jesus raised the report, and his relatives were persuaded to believe it to be true.
He is beside himself - He is delirious or deranged. The reason why this report gained any belief was, probably, that he had lived among them as a carpenter; that he was poor and unknown; and that now, at 30 years of age, he broke off from his occupations, abandoned his common employment, spent much time in the deserts, denied himself the common comforts of life, and set up his claims to be the Messiah who was expected by all the people to come with great pomp and splendor. The charge of "derangement" on account of attention to religion has not been confined to the Saviour. Let a man be made deeply sensible of his sins, and spend much of his time in prayer, and have no relish for the ordinary amusements or business of life; or let a Christian be much impressed with his obligation to devote himself to God, and "act" as if he believed there was an "eternity," and warn his neighbors of their danger; or let a minister show uncommon zeal and spend his strength in the service of his Master, and the world is not slow to call it derangement. And none will be more ready to originate or believe the charge than an ungodly and infidel parent or brother, a self-righteous Pharisee or professor in the church. At the same time, men may endanger themselves on the bosom of the deep or in the bowels of the earth for wealth; or may plunge into the vortex of fashion, folly, and vice, and break in upon the hours of repose, and neglect their duties to their family and the demands of business, and in the view of the world it is wisdom and proof of a sane mind! Such is the consistency of boasted reason; such the wisdom and prudence of worldly men!
Other Barnes' Notes entries containing Mark 3:21:
Jeremiah 12:5-6
John 7:4-5
1 Corinthians 9:5
2 Corinthians 5:13
1 Peter 4:4
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