Romans 1:28

What is the conscience going to be like that is in a debased mind? Their vain reasoning led to foolishness. I think what undoubtedly happened was that they did not want to retain God in their knowledge, and so God just let them do their thing. What resulted then was a reprobate mind whose standards permitted such things. A reprobate mind is a mind devoid of judgment. How trustworthy is a mind that cannot judge properly? How can it judge properly if it does not have the right standards?

What follows in the remaining portions of this chapter tell then the action that follows when standards other than God's are substituted in place of God's because God is left out of one's knowledge.

Think of this in terms of a cultural thing. As each person is born, his mind accepts what is a part of that culture, and his conscience adapts. What kind of action then follows? The same things that we see listed here at the end of Romans 1 are what follow. There is one additional thing. Because the tendency of human nature is downward, especially in a culture in which God is not a part, each generation takes it one step lower. That is why Paul could constantly say that evil men shall grow worse and worse.