Commentaries:
Barnes' Notes
Continue in prayer - That is, do not neglect it; observe it at all stated times; maintain the spirit of prayer, and embrace all proper occasions to engage in it; compare the Luke 18:1 note; Ephesians 6:18 note; I Thessalonians 4:17 note.
And watch in the same with thanksgiving - Watch for favorable opportunities; watch that your mind may be in a right frame when you pray: and watch, that when your mind is in a right frame you may not neglect to pray; see the Ephesians 6:18 note; Philippians 4:6.
Other Barnes' Notes entries containing Colossians 4:2:
Acts 1:14
Romans 12:12
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