That is, iniquity. The Greek word is anomia. It means against law. Thus, those who are not obedient, or those who did not make the right choices. They choose death. Most people on the face of this earth are on that broad path that is leading to destruction.
I think that is very clear. Our keeping of the commandments (which is love) is our response to God's love - first to Him, and then out to our fellow man.
What is the way to understand God, and to understand His way? It is to obey Him. As the psalmist says: