And it came to pass
The spiritual experience of Abraham was marked by four great crises, each of which involved a surrender of something naturally most dear. These were:
(1) Country and kindred Genesis 12:1; Matthew 10:34-39; II Corinthians 6:14-18
(2) His nephew, Lot; especially dear to Abraham by nature, as a possible heir and as a fellow believer II Peter 2:7,8; Genesis 13:1-18. The completeness of Abraham's separation from one who, though a believer, was a "vessel unto dishonour," is shown by ; Genesis 15:1-3; II Timothy 2:20,21; Acts 15:36-40.
(3) His own plan about Ishmael Genesis 17:17,18; I Chronicles 13:1-14; 15:1,2.
(4) Isaac, "thy son, thine only son Isaac, whom thou lovest" Genesis 22:1-19; Hebrews 11:17,18.
Other Scofield entries containing Genesis 22:1:
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