In this instance, the violent Sodomites, determined to assault Lot and his angelic guests sexually, were physically blinded. God used the two angels He had sent to deliver Lot as instruments to take the men's sight.
Angels are not the only servants of God used to blind those who oppose Him. On occasion, His human servants have prayed for Him to restrain the sight of enemies, and He has answered. For example, Elisha asked for God to blind the Syrian army, and He did so temporarily (II Kings 6:18-20). In Acts 13:11, Paul called on God to blind Elymas the sorcerer for a time, which He did. Famously, Christ Himself struck Paul blind on the road to Damascus, and the apostle's temporary blindness potently portrayed the spiritual blindness in which he walked to that point (Acts 9:3-9).
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