Commentaries:
Jamieson, Fausset, and Brown
not in their hand—but in the hand of God. This is Job's difficulty, that God who has sinners prosperity (good) in His hand should allow them to have it.
is—rather, "may the counsel of the wicked be far from me!" [UMBREIT]. This naturally follows the sentiment of the first clause: Let me not hereby be thought to regard with aught but horror the ways of the wicked, however prosperous.
Other Jamieson, Fausset, and Brown entries containing Job 21:16:
Job 22:18
Job 24:18-21
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