Commentaries:
David's enemies were physical people. Our enemies, however, are Satan, his distracting world, and our human nature, which he has been molding in his image since our births. If we are not to "fall and perish," these enemies must be vanquished—it comes down to "them or us." If God does not fight the battle, we will ultimately lose because our flesh is weak; we have little spiritual power against our enemies, especially Satan and his devices (John 15:5). Striving to pray always puts us in His presence at every opportunity, and our enemies' power over us recedes and eventually disappears.
Pat Higgins
Praying Always (Part Four)