Commentaries:
Jamieson, Fausset, and Brown
Therefore say I unto you, The kingdom of God—God's visible Kingdom, or Church, upon earth, which up to this time stood in the seed of Abraham.
shall be taken from you, and given to a nation bringing forth the fruits thereof—that is, the great evangelical community of the faithful, which, after the extrusion of the Jewish nation, would consist chiefly of Gentiles, until "all Israel should be saved" (Romans 11:25-26). This vastly important statement is given by Matthew only.
Other Jamieson, Fausset, and Brown entries containing Matthew 21:43:
Song of Solomon 8:11
Isaiah 5:6
Daniel 9:27
Amos 8:11
Matthew 3:9
Matthew 21:32
Luke 20:16
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