Commentaries:
John Wesley's Notes
This was done upon the sixth day, as was also the placing of Adam in paradise, though it be here mentioned after an account of the seventh day's rest: but what was said in general, Genesis 1:27, that God made man male and female is more distinctly related here, God caused the sleep to fall on Adam, and made it a deep sleep, that so the opening of his side might be no grievance to him: while he knows no sin, God will take care he shall feel no pain.
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