The meaning of Destruction in the Bible
(From International Standard Bible Encyclopedia)

de-struk'-shun: In the King James Version this word translates over 30 Hebrew words in the Old Testament, and 4 words in the New Testament. Of these the most interesting, as having a technical sense, is 'abhaddon (from verb 'abhadh, "to be lost," "to perish"). It is found 6 times in the Wisdom Literature, and nowhere else in the Old Testament; compare Revelation 9:11.

See ABADDON.

DESTRUCTION, CITY OF; HELIOPOLIS or CITY OF THE SUN

(Isaiah 19:18).

See ASTRONOMY, sec. I, 2; IR-HA-HERES; ON.

See more on the meaning of Destruction in the Bible:
Destruction {Easton's Bible Dictionary}

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