The meaning of Issue (of Blood) in the Bible
(From International Standard Bible Encyclopedia)

(zobh, zubh; rhusis, haimorrhoos): When used as a description of a bodily affection the word signifies: (1) A discharge, the consequence of uncleanness and sin (Leviticus 15:2 ff.; Numbers 5:2). As such it was one of the judgments which were to afflict the family of Joab (II Samuel 3:29); (2) a hemorrhage, either natural (Leviticus 12:7, where the word used is maqor, literally, a "fountain"), or the consequence of disease (Matthew 9:20; Mark 5:25; Luke 8:43).

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