The meaning of Ail in the Bible
(From International Standard Bible Encyclopedia)

al (Anglo-Saxon: eglan, "to pain"): As a verb translation, is "to trouble," "afflict" (obsolete); intrans, "to feel pain, trouble, uneasiness," etc.; it represents Hebrew mah lekha "what to thee" (Genesis 21:17, "What aileth thee, Hagar?"; Judges 18:23; I Samuel 11:5; II Samuel 14:5; II Kings 6:28; Isaiah 22:1); in Psalms 114:5, it is figuratively or poetically applied to the sea, the river Jordan, etc.: "What ailed thee, O thou sea, that thou fleddest?" etc.; the Revised Version (British and American), "What aileth thee, O thou sea that thou fleest?" etc.; in 2 Esdras 9:42; 10:31, "What aileth thee?"

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